Starting a Small Business in South Carolina

Welcome to the Small Business Startup South Carolina Franchise Directory! Here, you'll find everything you need to begin your journey to business ownership in the Palmetto State. If you're considering starting a small business in South Carolina, read on for an overview of the state economy. Afterward, explore business opportunities and franchises for sale with our South Carolina Franchise Search Tool.

Explore Opportunities and Insights

Sort by

Batteries Plus

Over 30 years of consistent growth. Ongoing support. Multiple revenue streams. Whether youre looking into owning your very first store, or youre interested in adding to your existing franchise portfolio, Batteries Plus is here to help. Learn more about the costs, benefits, and available locations today

$100,000 Min Cash Required

ClaimTek Systems

Start a Medical & Dental Billing and Practice Management Business Work from anywhere, part-time or full-time, flexible schedule, huge profit margins Healthcare is the growth industry of the 21st century Read more about this exciting opportunity now

$20,000 Min Cash Required

NTV360

NTV 360 presents a turnkey digital advertising franchise opportunity that delivers a high-margin, recurring revenue model. NTV 360's model allows entrepreneurs to place indoor digital billboards in high-traffic venues, such as restaurants, gyms, and medical offices, at no cost to the business owner. Franchisees generate revenue by selling ad placements to local businesses, tapping into a proven advertising model that requires no employees, inventory, or storefront.

$30,000 Min Cash Required

PostalAnnex

Today's busy lifestyles demand the services PostalAnnex offers. Capitalize on this demand and open your own business After retiring from the printing business PostalAnnex founder Jack Lentz began working out of his home as a business consultant. He soon realized the need for mailing faxing copying shipping and other services to belong under one roof. As a result he created the first PostalAnnex store business franchise located next door to a post office in the University City neighborhood of San Diego CA. Our franchises serve a growing customer base of small and home-based businesses that lacks the resources our stores offer. Today's hectic lifestyle requires a one-stop service center for businesses that don't have an administrative assistant to take care of those daily errands. Saving our consumers time is what keeps them coming back. By being a local neighborhood business

$70,000 Min Cash Required

My Business Venture

My Business Venture gives you the ability to start an online business from your home. We provide you access up to 1 million products & you chose up to 2,500 you want to feature on your website MBVs 10 Price Guarantee on all items on your website ensures you will always be profitable & NEVER be undersold Includes enrollment in MBV University training program.

$10,000 Min Cash Required

Wayback Burgers

Wayback Burgers is a fast-growing, globally recognized burger franchise offering hand-crafted food in a modern, nostalgic setting. With flexible restaurant formats, strong brand appeal, and full franchisee support, its an ideal opportunity for entrepreneurs seeking a scalable, community-driven business. From real estate to marketing, franchisees receive comprehensive help every step of the way. Join a brand built on quality, simplicity, and lasting customer loyalty.

$250,000 Min Cash Required

This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Review our cookies information for more details.

We are asking for your phone number so the businesses you have requested more information from can call/text you to chat with you more about their opportunity. We do not share your phone number with anyone other than the specific businesses you are interested in learning more about.